Monday, October 8

SESSION 1: Background to the H3Africa Initiative
Chair: Charles Rotimi, NIH-Center for Research on Genomics and Global Health

9:00 a.m.

Overview of the H3Africa Initiative  
Charles Rotimi, NIH-Center for Research on Genomics and Global Health

9:15 a.m.

H3Africa: The Funders perspective
Pat Goodwin, Wellcome Trust

9:35 a.m.

H3Africa: The Funders perspective  
Eric Green, NIH-National Human Genome Research Institute

9:55 a.m.

Questions

SESSION 2: Wellcome Trust Research Network
Chair: Audrey Duncanson, Wellcome Trust

10:00 a.m.

10:25 a.m.

Genetics of Rheumatic Heart Disease & Molecular Epidemiology of Streptococcus Pyogenes Pharyngitis
Bongani Mayosi, University of Cape Town

10:50 a.m.

TrypanoGEN: An Integrated Approach to the Identification of Genetic Determinants of Susceptibility to Trypanosomiasis
Enock Matovu, Makerere University of Veterinary Medicine

11:15 a.m.

Coffee break

SESSION 3: NIH Collaborative Centres and Research Projects
Chair: Jane Peterson, NIH-National Human Genome Research Institute

11:45 a.m.

Genomic and Environmental Risk Factors for Cardiometabolic Disease in Africans 
Michele Ramsay, University of Witswatersrand & NHLS

12:10 p.m.

H3Africa Kidney Disease Research Network Organization
Dwomoa Adu, University of Ghana Medical School

12:35 p.m

Contribution of genetic variation to pharmacokinetic variability and toxicity in patients undergoing multi-drug tuberculosis treatment in Sub-Saharan Africa: RAFAgene project
Dissou Affolabi, National Hospital for Tuberculosis and Pulmonary Diseases, Benin 

1:00 p.m.

Lunch

SESSION 4: NIH Bioinformatics and Biorepository Projects
Chair: Mark Guyer, NIH-National Human Genome Research Institute

2:00 p.m.

Background to Bioinformatics Network
Jane Peterson, NIH-National Human Genome Research Institute 

2:10 p.m.

H3ABioNet: A sustainable African bioinformatics network for H3Africa
Nicola Mulder, Computational Biology Group, University of Cape Town

2:30 p.m.

Discussions

3:00 p.m.

Background to Biorepository Grants
Jane Peterson, NIH-National Human Genome Research Institute

3:10 p.m.

IHVN H3Africa Biorepository (I-HAB) Initiative

Alash'le G. Abimiku, Institute of Human Virology, Nigeria

3:30 p.m.

Development of H3 Africa Biorepositories to facilitate studies on Biodiversity, Disease and Pharmacogenomics of African Populations
Akin Abayomi, University of Stellenbosch

3:50 p.m.

Discussion

4:15 p.m

Tea Break

4:30 p.m.

Networking / Opportunity to find out more from commercial exhibitors

• Human Research Based on Next Generation Sequencing    
  Patric Tao Li, BGI-Europe
• Inqaba biotec: Africa's Genomics Company  
  Oliver Presig, Inqaba Biotechnical Industries (Pty) Ltd and Fabrice Wane, inqaba Biotec East Africa Ltd
• Roche Applied Science Solutions 
  Jonathan Keytel, Roche Applied Science

4:30 p.m.

Press Briefing

• Audio  [MP3 - 4 MB]
• Transcript

7:00 p.m

Drinks and Presentation: 

Leverage of Partnerships on Science, Technology and Innovation in Africa 
Diran Makinde, NEPAD Planning and Coordinating Agency

7:30 p.m.

Dinner

8:30 p.m.

After-dinner Talk: Enhanced Breeding of African Traditional Food Crops Utilizing NextGeneration Genomic Tools to Help End Chronic Hunger and Malnutrition
Howard-Yana Shapiro, Mars Incorporated

Tuesday, October 9

9:00 a.m.

Continuation of Biorepository Discussion
Alash'le G. Abimiku, Institute of Human Virology, Nigeria and Akin Abayomi, University of Stellenbosch

SESSION 5: Sharing Protocols and Data
Chairs: Rex Chisholm, Feinberg School of Medicine, Northwestern University
Carlos Bustamante, School of Medicine, Stanford University

9:15 a.m.

Lessons from other Genomics Projects
Mark Guyer, NIH-National Human Genome Research Institute

9:30 a.m

Sharing: the H3Africa Vision  
Charles Rotimi, NIH-National Human Genome Research Institute

9:50 a.m.

Discussion

10:00 a.m.

Sharing Protocols - Best Practices
Carlos Bustamante, School of Medicine, Stanford University

10:20 a.m.

Discussion

10:30 a.m.

Coffee Break

11:00 a.m.

Sharing Data - Best Practices  
Rex Chisholm, Feinberg School of Medicine, Northwestern University

11:20 a.m.

Discussion

11:30 a.m.

Breakout Groups

12:15 p.m.

Report Back

12:45 p.m.

Lunch

SESSION 6: Consent and Feedback of Results
Chairs: Ruth Chadwick, Cesagen, Cardiff University
Charmaine Royal, Duke Institute for Genome Sciences and Policy

1:45 p.m.

Consent: State of the Art and Issues Arising  
Ruth Chadwick, Cesagen, Cardiff University

2:05 p.m.

Returning Research Results: The Why, What, Where, When, How and Who?  
Charmaine Royal, Duke Institute for Genome Sciences and Policy

2:30 p.m.

Community Harms in Genomics Research in Africa  
Clement Adebamowo, Institute of Human Virology, Nigeria

2:50 p.m.

Discussion

3:30 p.m.

Tea Break

4:00 p.m.

Breakout Groups

4:45 p.m.

Report Back

5:30 p.m.

Opportunities for Networking and Discussion with Funders

• H3Africa: Building Capacity in Research Administration  
  Jean Flagg-Newton, NIH-National Institute for Child Health & Human Development

7:00 p.m.

Drinks

7:30 p.m.

Dinner

Wednesday, October 10

7:30 a.m.

Private Breakfast for H3Africa Independent Expert Committee Members and Funders

9:00 a.m.

Review of Day 2 and Introduction to Day 3
Pat Goodwin, Wellcome Trust

SESSION 7: Building Capacity Across the Network
Chairs: Solomon Nwaka, WHO-TDR
Ayoade Odoula, Institute for Infectious Diseases of Poverty (IIDP/IRMP), Nigeria

9:15 a.m.

Introductory Comments

• Sciences and Health in Africa: WHY Build Capacy for Genomics Research  
  Solomon Nwaka, WHO-TDR
  Ayoade Odoula, Institute for Infectious Diseases of Poverty, IIDP/IRMP, Nigeria
  Philip Awadalla, University of Montreal 
• H3ABioNet: Buiilding Capacity in Bioinformatics  
  Nicola Mulder, Computational Biology Group, University of Cape Town

10:15 a.m.

Discussion

11:00 a.m.

Coffee

11:30 a.m.

Breakout Groups

12:15 p.m.

Report Back

1:00 p.m.

Lunch

SESSION 8: The H3Africa Initiative - What will success look like?
Chairs: Pat Goodwin, Wellcome Trust and Eric Green, NIH-National Human Genome Research Institute

2:00 p.m.

Introductory Comments - Members of H3Africa Independent Expert Committee

2:00 p.m.

Discussion and Breakout Groups

3:30 p.m.

Review of Meeting and Next Steps

4:00 p.m.

Close of Meeting